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FDA Approves First Drug Specifically for Generalized Pustular Psoriasis

Dr. Ted Rosen details FDA-approved spesolimab as the first drug specifically indicated for the treatment of generalized pustular psoriasis flares in adults. Ted Rosen, MD, FAAD Editor-in-Chief Spesolimab (Spevigo, Boehringer Ingelheim Pharmaceuticals) is a humanized monoclonal IgG1 antibody directed against interleukin-36 (IL-36) signaling. This agent binds to IL-36R, thereby preventing activation of this receptor by ligands. […]