The “open sandwich” moisturizer method involves applying moisturizer before or after, rather than between, retinoids or retinol, and research suggests this approach won’t diminish the bioactivity of these ingredients and may even improve tolerability. Shanna M. Miranti, MPAS, PA-C, a Board-certified Physician Assistant at Riverchase Dermatology in Naples, FL, explains more about the “open sandwich” technique.
